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Not Just Women, Low Vitamin D Can Be Dangerous For Men Too
It isn't just women but lack of vitamin D can prove dangerous for men as well. Here is an article that explains the reasons.
Middle-age men with low levels of vitamin D and hormones associated with muscle- and bone-building may be more likely to develop decline in muscle mass and strength that causes frailty, a study has found.
Frailty is the gradual loss of energy, strength and physical capability that can come with ageing and often leads to dependency, disability and death.
The findings showed that having lower levels of vitamin D, insulin-like growth factor-1 (IGF-1) and its binding protein 3 (IGFBP3) were associated with a higher risk of frailty.
"With the ageing population, frailty-related problems present an increasing challenge to healthcare systems worldwide," said lead author Agnieszka Swiecicka, research student at the University of Manchester.
"Vitamin D, besides maintaining bone health, regulates muscle function and low vitamin D levels are linked to lower muscle mass and strength. IGF-1 affects muscle growth and repair and its action and levels are modified by its carrier protein IGFBP3," Swiecicka added.
The
results
were
presented
at
the
Endocrine
Society's
99th
annual
meeting
ENDO
2017
in
Orlando.
Further,
men
with
low
levels
of
anabolic
hormone
muscle
and
bone-building
hormone
were
found
to
have
higher
levels
of
frailty.
In addition, elderly men with lower levels of the hormone dehydroepiandrosterone sulfate (DHEA-S)which has direct anabolic effect on muscle mass were linked to a higher likelihood of worsening frailty.
"We showed novel associations between anabolic hormone levels and changes in frailty levels in ageing men, which could enable early identification of at-risk individuals and the development of new treatments and prevention strategies," Swiecicka said.
However, "this does not establish cause, and clinical trials will be required to find out if giving these hormones to middle-age and elderly men could prevent the development of frailty", she added.
With Inputs From IANS
Disclaimer: The information provided in this article is for general informational and educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or a qualified healthcare provider with any questions you may have regarding a medical condition.
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